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01.Complement Factor C1q [Human, 11 S-Component]
02.Complement Factor C1r [Human]
03.Complement Factor C2 [Human]

Complement Factors

The complement system is a biochemical cascade that helps clear pathogens from an organism. It is part of the larger immune system that is not adaptable and does not change over the course of an individual's lifetime; as such it belongs to the innate immune system. However, it can be recruited and brought into action by the adaptive immune system. The complement system consists of a number of small proteins found in the blood, normally circulating as inactive zymogens. When stimulated by one of several triggers, proteases in the system cleave specific proteins to release cytokines and initiate an amplifying cascade of further cleavages. The end-result of this activation cascade is massive amplification of the response and activation of the cell-killing membrane attack complex. Over 20 proteins and protein fragments make up the complement system, including serum proteins, serosal proteins, and cell membrane receptors. These proteins are synthesized mainly in the liver, and they account for about 5% of the globulin fraction of blood serum.
 Model   Product Name+ 
 10-14-1101   Complement Factor C1q [Human, 11 S-Component] 
 10-14-1111   Complement Factor C1r [Human] 
 10-14-1121   Complement Factor C1s [C1-Esterase] 
 10-14-1102   Complement Factor C2 [Human] 
 10-14-1103   Complement Factor C3 [Human, beta 1 C-Globulin] 
 10-14-1104   Complement Factor C4 [Human, beta 1 C-Globulin] 
 10-15-1102   Complement Factor B [CFB, Properdin, C3 Proactivator] 
 10-14-1114   Complement Factor C4 - Binding Protein [Human] 
 10-14-1105   Complement Factor C5 [Human, beta 1 F-Globulin] 
 10-15-1104   Complement Factor D [CFD, Adipisin, C3 Activator Convertase] 
 10-15-1106   Complement Factor H [CFH, b1h Globulin] 
 10-15-1107   Complement Factor I [CFI, Cb3/Cb4 - Inactivator] 
 10-15-1108   Complement Factor P [CFP, Properdin] 
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