Biopur - High Quality Human and Animal Proteins,Enzymes and Reagents

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01.	α₂-Macroglobulin [Human, α₂-M]
02.	Aprotinin [Bovine] - Agarose
03.	α₁-Antitrypsin [Human] - Agarose
04.	α₁-Antitrypsin [Human, α₁-Proteinase Inhibitor]
05.	Angiostatin [Human Plasma]
06.	Antithrombin III [Human, AT III, Heparin Cofactor, Factor Xa Inhibitor]
07.	Antithrombin III [Human] - Agarose
08.	Hirudin - Agarose
09.	Pepstatin A - Agarose

Inhibitors


Enzyme inhibitors are molecules that bind to enzymes and decrease their activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. They are also used as herbicides and pesticides. Not all molecules that bind to enzymes are inhibitors; enzyme activators bind to enzymes and increase their enzymatic activity. The binding of an inhibitor can stop a substrate from entering the enzyme's active site and/or hinder the enzyme from catalysing its reaction. Inhibitor binding is either reversible or irreversible. Irreversible inhibitors usually react with the enzyme and change it chemically. These inhibitors modify key amino acid residues needed for enzymatic activity. In contrast, reversible inhibitors bind non-covalently and different types of inhibition are produced depending on whether these inhibitors bind the enzyme, the enzyme-substrate complex, or both. Many drug molecules are enzyme inhibitors, so their discovery and improvement is an active area of research in biochemistry and pharmacology. A medicinal enzyme inhibitor is often judged by its specificity (its lack of binding to other proteins) and its potency (its dissociation constant, which indicates the concentration needed to inhibit the enzyme). A high specificity and potency ensure that a drug will have few side effects and thus low toxicity.

Model	Product Name+
10-20-1108	α₁-Antichymotrypsin [Human ACT, from Plasma]
10-20-4104	α₁-Antitrypsin [Human] - Agarose
10-20-1103	α₂-Antiplasmin [Human Plasma]
10-20-1105	α₂-Macroglobulin [Human, α₂-M]
10-20-1104	α₁-Antitrypsin [Human, α₁-Proteinase Inhibitor]
10-20-4105	α₂-Macroglobulin - Agarose
15-20-1101	4-(2-Aminoethyl)-Benzenesulfonylfluoride Hydrochloride [AEBSF]
10-71-1103	Angiostatin [Human Plasma]
10-20-1102	Antithrombin III [Human, AT III, Heparin Cofactor, Factor Xa Inhibitor]
10-20-4102	Antithrombin III [Human] - Agarose
11-20-1001	Aprotinin [Bovine, Kallikrein Inactivator]
11-20-4001	Aprotinin [Bovine] - Agarose
10-20-1102.3	AT III [Human, Heparin Cofactor, Factor Xa Inhibitor, Antithrombin III]
14-20-1108	Endostatin [Recombinant Human]
10-20-1102.1	Factor Xa Inhibitor [Human, AT III, Heparin Cofactor, Antithrombin III]
10-20-1132	Heparin Cofactor II [Human]
10-20-1102.2	Heparin Cofactor [Human, AT III, Factor Xa Inhibitor, Antithrombin III]
11-20-4152	Hirudin - Agarose
11-20-1152	Hirudin [Hirudo Medicinalis, High Activity]
10-20-1112	Inter-α₁-Trypsin Inhibitor [Human Plasma]
13-22-4105	Pepstatin A - Agarose
13-22-1105	Pepstatin A [Microbial]

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